Astute Ventures

A Global Vaccine Developer and Manufacturer

• GPN Vaccine covers all 100 Serotypes of Pneumonia and all future Serotypes.
• Pneumonia is a common respiratory infection, affecting approximately 450 million people a year and occurring in all parts of the world. It is a major cause of death among all age groups, resulting in 1.4 million deaths in 2010 (7% of the world’s yearly total) and 3.0 million deaths in 2016 (the 4th leading cause of death in the world)
• Pneumonia is the leading cause of death for children under 5 — more than 800,000 children died due to pneumonia in 2017.
• The global mortality rates for older people remained unchanged since 1990.
• Mortality from pneumonia is highest in Sub-Saharan Africa.
• The greatest risk factors for developing pneumonia are undernutrition, air pollution and smoking.
• Research suggests that pneumococcal vaccines could be saving the lives of almost 400,000 children annually.

LYRIC BIO – Next Generation Therapeutics Manufacturing

https://www.lyricbio.com/

Lyric Bio, Inc. is expanding biomanufacturing to human donor-derived biologics.

Using proprietary tissue engineering technology Lyric is developing high-density tissue mimicking bioreactors that will reduce Ig therapy dependence on human donation by several orders of magnitude.

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The Biotechnology Revolution was enabled by advances in biomanufacturing.

At Lyric our vision is eliminate global shortages of critical therapeutics by enabling scalable manufacturing of complex therapeutics. Today, access to life-saving medicines like insulin and monoclonal antibodies are taken for granted; however, just 50 years ago their use was severely limited because no means of scalable manufacturing existed.

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Millions of people still rely on medical treatment dependent on human donations. 

Standard biomanufacturing processes cannot produce complex therapeutics. This results in high cost and limited access to life-saving therapies. Lyric is solving this problem. We are starting with a life-saving therapeutic used to treat over 100 different diseases, human immunoglobulin (IvIg, ScIg). 

Rarefied BIO

Rarefied Biosciences is committed to improve the lives of patients suffering from immune diseases.